Our Story

Cropped — Girl With Walker

Cerebral Palsy Alliance Research Foundation (CPARF) is the foremost nonprofit organization in the world focusing on research and innovation for people with cerebral palsy.

CP is the most common lifelong physical disability in the world, affecting 1 million people in the US and 18 million people worldwide. It’s a diverse disability that demands a diverse research portfolio, and we steadfastly support research that serves the whole community. We start at Day One with the earliest interventions to potentially lessen CP’s severity or prevent the injury that causes it. We keep going with science that will make it more comfortable for children to get the therapies they need. We continue with research that will uncover new chronic pain treatments for adults. We proudly champion research for every age and every stage.


In the US, CP research is currently trapped in a cycle of chronic underinvestment that stifles innovation. The National Institutes of Health (NIH) only allocates around $28 million to CP research annually of their $41.7 billion annual budget, despite CP’s high prevalence and exceptionally high lifelong economic burden. Approximately one in 323 babies is diagnosed with CP each year, and related average lifetime costs exceed $1.2 million per person. Less common disabilities with lower lifetime costs receive exponentially more NIH funds than CP, leading to more research for those conditions.


CPARF will change that through strategic funding directed to five research priorities:

• Early detection and early intervention
• Chronic pain
• Technology
• Regenerative medicine
• Genomics

We have given out US-based grants totaling $44.4 million to date and robust private funding will help us attract the brightest researchers and advance promising science to the critical clinical trial stage.

CP was once thought of as unchangeable and we’re changing the way people think.

Your generosity can do even more. When you support our research, innovation, and implementation initiatives, you will change lives — and you will bring science to life to change what’s possible for people with cerebral palsy.